Overview Guillain-Barré Syndrome (GBS) is an acute, immune-mediated polyneuropathy typically triggered by a preceding gastrointestinal or respiratory infection. It is characterised by an autoimmune attack on the peripheral nerves, leading to mainly demyelination but also axonal degeneration, which impairs nerve conduction and causes muscle weakness and paralysis. GBS affects about 1–2 per 100,000 people annually. […]