Sjögren’s Syndrome Quiz

A patient has chronic dry eyes and dry mouth, and Sjögren syndrome is suspected. Which test most directly confirms the diagnosis?

Which autoantibody is most characteristic of Sjögren syndrome?

Which clinical feature suggests a high risk of lymphoma in a patient with Sjögren’s syndrome?

Which renal problem is most commonly associated with Sjögren syndrome?

A patient with Sjögren syndrome has bothersome dry eyes. What is the most appropriate initial management?

Which feature is most consistent with primary Sjögren syndrome rather than secondary Sjögren syndrome?