Overview Myasthenia Gravis (MG) is a chronic autoimmune neuromuscular disorder where antibodies target acetylcholine receptors (AChR) or MuSK proteins at the post-synaptic membrane, impairing neuromuscular transmission and causing muscle weakness Myasthenia Gravis (MG) is a rare autoimmune disorder marked by fluctuating muscle weakness that worsens with activity and improves with rest, commonly affecting the ocular […]

Overview Guillain-Barré Syndrome (GBS) is an acute, immune-mediated polyneuropathy typically triggered by a preceding gastrointestinal or respiratory infection. It is characterised by an autoimmune attack on the peripheral nerves, leading to mainly demyelination but also axonal degeneration, which impairs nerve conduction and causes muscle weakness and paralysis. GBS affects about 1–2 per 100,000 people annually. […]

Overview Transient ischemic attack is defined as transient neurologic symptoms without evidence of acute infarction. It is a common and important risk factor for future stroke. TIAs are produced by temporary ischemia to a vascular territory, usually caused by thrombosis or embolism and less commonly by vasculitis, hematologic disorders such as sickle cell disease or […]

Overview Third most common cause of death worldwide and most common cause of neurological disability. It is subdivided into ischaemic stroke (caused by vascular occlusion or stenosis) and haemorrhagic stroke (caused by vascular rupture, resulting in intra-parenchymal and/or subarachnoid haemorrhage). Anatomy and Phsyiology Cerebral anatomy and blood supply Sensory Pathways Motor Pathways Aetiology and Risk Factors Aetiology […]

Overview Cerebral palsy is a non-Progressive neurological disorder. Usually with significant motor component. Clinical presentation overtime changes due to increased developmental challenges.Cerebral palsy (CP) is the most common physical disability in childhood. Prevalence is about 1 – 3/ 1000 live births. Cerebral palsy can affect: Anatomy and Physiology of the Motor Nervous system Classification Cerebral […]

“Each patient ought to feel somewhat the better after the physician’s visit irrespective of the nature of the illness.” -Warfield Theobald Longcope Overview Multiple sclerosis (MS) is defined as an inflammatory demyelinating disease characterised by the presence of episodic neurological dysfunction in at least 2 areas of the CNS (brain, spinal cord, and optic nerves) […]

Overview Parkinson’s disease is a progressive neurodegenerative disorder characterised by tremor, rigidity, bradykinesia, and a wide spectrum of non-motor symptoms including sleep disorders, hyposmia, bladder and bowel dysfunction, fatigue, dementia, and other neuropsychiatric symptom. Although the disease has no cure, available treatments effectively control motor symptoms and improve quality of life. Parkinson disease affects approximately 1 […]