Glutathione is a tripeptide composed of glutamine, cysteine, and glycine, serving as a critical antioxidant in the body, protecting cells from oxidative stress and maintaining redox balance. Its clinical significance lies in its role in detoxification processes, immune function, and cellular repair, making it vital in conditions like liver disease and cancer. A key association is its depletion in chronic illnesses, which can exacerbate oxidative damage and impair healing.