About this video
Immune-mediated vasculitis: how inflammation damages arteries, causes palpable purpura, ischemia, stenosis, and aneurysms. Learn the core pathophysiology of vasculitis and the immune mechanisms driving vessel injury, including antigen presentation, molecular mimicry, immune complex deposition, ANCA-driven neutrophil activation, complement-mediated damage, and granulomatous inflammation. This clear, clinically focused video explains classification by vessel size (large, medium, small), why small- and medium-vessel disease produces cutaneous findings like palpable purpura, and how endothelial injury leads to fibrinoid necrosis, thrombosis, and long-term fibrosis. Viewers will…
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