Medium-sized vessel vasculitis refers to a group of inflammatory disorders affecting medium-sized arteries, leading to vessel wall damage and potential organ ischemia. It is clinically significant as it can result in serious complications, such as aneurysm formation or organ dysfunction, if not promptly diagnosed and treated. A key example is Polyarteritis nodosa, which is associated with systemic symptoms and can affect multiple organ systems, necessitating early intervention.

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