NT-proBNP (N-terminal pro b-type Natriuretic Peptide) is a biomarker released by the heart in response to ventricular wall stress, primarily in conditions like heart failure. It is clinically significant as elevated levels indicate heart dysfunction and help differentiate cardiac from non-cardiac causes of dyspnoea. A key association is its elevation in acute heart failure, where it aids in diagnosis, prognosis, and guiding treatment decisions.

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