Erythema nodosum

Erythema nodosum is a painful inflammatory condition characterised by the formation of tender, red nodules, usually located on the lower legs. It is significant in clinical practice as it often indicates an underlying systemic condition, such as infections, autoimmune diseases, or drug reactions, necessitating further investigation. A key association is with sarcoidosis, where erythema nodosum may serve as a clinical marker of the disease's presence or activity.