Soft-tissue calcifications refer to the abnormal deposition of calcium salts in non-bony tissues, often seen on imaging studies. They are clinically significant as they can indicate underlying pathological processes, such as inflammation, necrosis, or malignancy, and may influence diagnosis and treatment decisions. A common example is dystrophic calcification in areas of chronic tissue damage, such as in atherosclerotic plaques, which can lead to cardiovascular complications.
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