Cartilage degeneration refers to the progressive deterioration of cartilage tissue, often characterised by loss of structural integrity, hydration, and elasticity, leading to joint pain and dysfunction. This condition is clinically significant as it underlies common musculoskeletal disorders, such as osteoarthritis, which can severely impact a patient's quality of life and mobility. A key association is the age-related wear and tear on cartilage, which increases the risk of joint-related complications.