Chronic degeneration

Chronic degeneration refers to the progressive deterioration of tissue or organ function over an extended period, often resulting from persistent injury, inflammation, or metabolic imbalances. This condition is clinically significant as it can lead to functional impairment and increased morbidity, necessitating ongoing management strategies. A key example is osteoarthritis, where chronic degeneration of joint cartilage results in pain, stiffness, and reduced mobility.