The cytochrome P450 enzyme system comprises a family of enzymes that play a crucial role in the metabolism of various substances, including drugs, toxins, and endogenous compounds. Its clinical significance lies in its influence on drug pharmacokinetics, affecting drug efficacy and safety, as well as the potential for drug interactions. For example, variations in CYP2D6 can lead to altered responses to medications like antidepressants, highlighting the importance of personalised medicine.
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