A fibroatheroma is an advanced atherosclerotic plaque characterised by a lipid-rich necrotic core covered by a fibrous cap within the arterial wall. It is clinically significant because its structural integrity influences the risk of plaque rupture, which can precipitate acute coronary syndromes. A thin fibrous cap overlying a large necrotic core is particularly prone to rupture, leading to thrombosis and myocardial infarction.
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