A gastrointestinal ulcer is a localized erosion of the gastrointestinal mucosa, most commonly occurring in the stomach (gastric ulcer) or the duodenum (duodenal ulcer). These ulcers are clinically significant as they can lead to complications such as gastrointestinal bleeding, perforation, and obstruction, necessitating prompt diagnosis and management. A key association is the infection with Helicobacter pylori, which is a major contributor to ulcer formation and recurrence.