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Armando Hasudungan

Hepatic injury

Hepatic injury refers to damage to liver cells, which can result from various factors including toxins, infections, or underlying diseases. It is clinically significant as it can lead to liver dysfunction, impacting metabolism, detoxification, and synthesis of vital proteins, potentially progressing to liver failure. A key association is with drug-induced liver injury, where medications like paracetamol can cause severe hepatotoxicity, necessitating prompt recognition and management.

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