Recurrent pregnancy loss

Recurrent pregnancy loss is defined as the occurrence of two or more consecutive clinical pregnancies that end in miscarriage before 20 weeks of gestation. It is clinically significant as it can indicate underlying health issues, such as chromosomal abnormalities, uterine anomalies, or autoimmune disorders, necessitating thorough investigation and management. One key association is antiphospholipid syndrome, which can lead to increased risk of thrombosis and adverse pregnancy outcomes.