SpO2, or peripheral capillary oxygen saturation, is a measure of the percentage of oxygen-saturated haemoglobin in the blood, typically assessed using a pulse oximeter. It is crucial in clinical practice as it helps evaluate a patient's respiratory function and oxygen delivery, guiding interventions in conditions like chronic obstructive pulmonary disease (COPD) or during anaesthesia. A SpO2 level below 90% indicates hypoxaemia, necessitating immediate assessment and potential oxygen therapy.

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