Takayasu arteritis is a rare, large-vessel vasculitis primarily affecting young women, characterised by inflammation of the aorta and its major branches, leading to stenosis, occlusion, or aneurysm formation. It is clinically significant due to its potential to cause severe complications such as hypertension, limb ischemia, and stroke, necessitating early diagnosis and management. A key association is the presence of systemic symptoms like fever and fatigue, which can precede vascular manifestations.