Hyperosmolarity refers to a condition where the osmolarity of body fluids is elevated, typically above 300 mOsm/L, indicating a higher concentration of solutes such as glucose or electrolytes. This condition is clinically significant as it can lead to cellular dehydration, affecting organ function and potentially resulting in complications like hyperosmolar hyperglycaemic state (HHS) in uncontrolled diabetes, which can be life-threatening if not promptly treated.

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