Hydrochlorothiazide

Hydrochlorothiazide is a thiazide diuretic commonly used to manage hypertension and reduce fluid retention in conditions such as heart failure and oedema. It works by inhibiting sodium reabsorption in the distal convoluted tubule of the nephron, leading to increased urine output and decreased blood volume. A key association is its potential to cause electrolyte imbalances, particularly hypokalemia, which can lead to cardiac complications if not monitored.