Central obesity

Central obesity refers to the accumulation of excess fat around the abdomen and trunk, often assessed using waist circumference or waist-to-hip ratio. It is clinically significant as it is associated with an increased risk of metabolic syndrome, cardiovascular disease, and type 2 diabetes due to its impact on insulin resistance and inflammatory processes. A key complication of central obesity is the development of non-alcoholic fatty liver disease, which can lead to severe liver dysfunction.