Pramlintide is a synthetic analogue of amylin, a hormone co-secreted with insulin by pancreatic beta cells, used as an adjunct treatment for type 1 and type 2 diabetes. It helps regulate postprandial glucose levels by slowing gastric emptying, reducing glucagon secretion, and promoting satiety, which can aid in weight management. A key association is its potential to cause hypoglycaemia when used with insulin, necessitating careful monitoring of blood glucose levels.
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