Anti-TNF agents are biologic medications that inhibit tumour necrosis factor-alpha (TNF-α), a pro-inflammatory cytokine involved in autoimmune diseases. They are crucial in managing conditions like rheumatoid arthritis, inflammatory bowel disease, and psoriasis by reducing inflammation and preventing joint damage. A key example is infliximab, which can lead to complications such as increased risk of infections due to immunosuppression.

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