Aquaporin 2

Aquaporin 2 (AQP2) is a water channel protein primarily located in the renal collecting ducts, playing a crucial role in water reabsorption and maintaining body fluid balance. Its regulation is essential in conditions such as diabetes insipidus, where impaired AQP2 function leads to excessive urination and dehydration. Understanding AQP2's mechanisms is vital for developing targeted therapies for fluid balance disorders and enhancing patient management in renal and endocrine conditions.