Chronic kidney injury (CKI) is a progressive loss of kidney function over three months or more, characterised by a decrease in glomerular filtration rate (GFR) and/or evidence of kidney damage. It is clinically significant as it increases the risk of cardiovascular disease, necessitates careful management of comorbidities, and may lead to end-stage renal disease requiring dialysis or transplantation. A common complication of CKI is hyperkalaemia, which can cause life-threatening cardiac arrhythmias.
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