Enhanced automaticity

Enhanced automaticity refers to an increased ability of cardiac cells, particularly pacemaker cells, to spontaneously depolarise and generate action potentials. This phenomenon is clinically significant as it can lead to arrhythmias, such as atrial fibrillation, which may result in hemodynamic instability or thromboembolic events. Conditions like hypoxia, electrolyte imbalances, or certain medications can precipitate enhanced automaticity, necessitating careful monitoring and management in affected patients.