Fibrinogen

Fibrinogen is a soluble plasma glycoprotein produced by the liver, essential for blood coagulation. Upon vascular injury, it is converted into fibrin by thrombin, forming a mesh that stabilises blood clots, thus preventing excessive bleeding. Clinically, abnormal fibrinogen levels can indicate various conditions, such as disseminated intravascular coagulation (DIC), where excessive clotting leads to organ dysfunction and bleeding complications.