The hepatic artery is a major blood vessel that supplies oxygenated blood to the liver, branching from the common hepatic artery, which itself arises from the celiac trunk. Its significance in clinical practice lies in its role in liver function and metabolism, making it crucial during liver surgeries and in conditions such as hepatic artery thrombosis, which can lead to ischemia and liver damage. Understanding its anatomy is essential for interventions like liver transplants and managing hepatic diseases.