Hereditary motor and sensory neuropathies

Hereditary motor and sensory neuropathies (HMSNs) are a group of inherited disorders affecting peripheral nerves, leading to muscle weakness and sensory loss. Clinically significant due to their impact on mobility and quality of life, these conditions can complicate diagnosis and management in neurology. Charcot-Marie-Tooth disease, a common form of HMSN, exemplifies the diverse genetic mutations involved and highlights the importance of genetic counselling in affected families.