Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade various components of the extracellular matrix, playing a crucial role in tissue remodelling, repair, and inflammation. Their dysregulation is implicated in numerous pathological conditions, including cancer metastasis and chronic inflammatory diseases. For instance, elevated MMP levels are often associated with rheumatoid arthritis, contributing to joint destruction and disease progression.
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