Pertactin is an outer membrane protein found in Bordetella pertussis, the bacterium responsible for whooping cough. It plays a crucial role in the pathogen's ability to adhere to respiratory epithelial cells, facilitating infection. Understanding pertactin is vital for developing effective vaccines and diagnostic tests, as well as for monitoring vaccine effectiveness, given that some strains of B. pertussis may lack this protein, potentially leading to vaccine escape.
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