Syndrome of Inappropriate Antidiuretic Hormone secretion (SIADH) is a condition characterised by excessive release of antidiuretic hormone (ADH), leading to water retention, hyponatraemia, and dilutional hypervolaemia. It is clinically significant as it can cause neurological symptoms due to low serum sodium levels and may complicate the management of various underlying conditions, such as malignancies or central nervous system disorders. Prompt recognition and treatment are essential to prevent serious complications.

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