System: Immune System

Learn about myasthenia gravis, an autoimmune neuromuscular disorder characterized by fluctuating muscle weakness due to impaired neuromuscular transmission. This video covers its symptoms, underlying pathophysiology, diagnostic investigations, and available treatment…

Learn about Lambert-Eaton Myasthenic Syndrome (LEMS), a rare autoimmune disorder affecting neuromuscular transmission due to impaired calcium channel function. This video explains its pathophysiology, hallmark signs such as proximal muscle…

Explore the life cycle and pathophysiology of Human Immunodeficiency Virus (HIV), from viral entry and replication to immune system destruction. This video also covers diagnostic tests, clinical investigations, and how…

There are two main types of transplant rejection; T cell mediated and antibody mediated and antibody mediated transplant rejection. These rejections are divided into hyperacute, acute and chronic rejection. In…

Explore the link between declining CD4+ cell counts and the development of opportunistic infections and AIDS-defining illnesses in HIV-positive individuals. This video outlines common infections and malignancies, diagnostic clues, and…

Discover hypersensitivity pneumonitis, an immune-mediated lung condition triggered by inhaled environmental antigens. This video explains its pathophysiology, clinical signs, diagnostic approach, and strategies for management including antigen avoidance and medical…

Glucocorticoids are used in many inflammatory, autoimmune conditions. While being used to treat an underlying disease gluocorticoids are associated with an appreciable risk of bone loss and increases risk of…

Hemophagocytic lymphohistiocytosis (HLH) explained: learn causes, signs, tests, and life-saving treatments. This video breaks down HLH, a hyperinflammatory syndrome where overactive macrophages and cytotoxic T/NK cells trigger a cytokine storm…

George syndrome (22q11.2 deletion) and Job syndrome (hyper-IgE) explained with clear clinical signs and immune defects. Learn how these well-defined genetic syndromes cause recurrent infections, immune dysfunction, and characteristic physical…

Explore Chediak-Higashi Syndrome, a rare autosomal recessive disorder affecting lysosomal trafficking and immune cell function. This video explains its genetic basis, characteristic features like recurrent infections and albinism, and the…