Glucocorticoids are used in many inflammatory, autoimmune conditions. While being used to treat an underlying disease gluocorticoids are associated with an appreciable risk of bone loss and increases risk of…

Hemophagocytic lymphohistiocytosis (HLH) explained: learn causes, signs, tests, and life-saving treatments. This video breaks down HLH, a hyperinflammatory syndrome where overactive macrophages and cytotoxic T/NK cells trigger a cytokine storm…

George syndrome (22q11.2 deletion) and Job syndrome (hyper-IgE) explained with clear clinical signs and immune defects. Learn how these well-defined genetic syndromes cause recurrent infections, immune dysfunction, and characteristic physical…

Explore Chediak-Higashi Syndrome, a rare autosomal recessive disorder affecting lysosomal trafficking and immune cell function. This video explains its genetic basis, characteristic features like recurrent infections and albinism, and the…

Achalasia is a rare disorder that results from progressive destruction of ganglion cells in the myenteric plexus of the oesophageal wall. The destruction of these cells leads to the inability…

Mycophenalate is used in lupus nephritis (first line), diffuse SS but also indicated for the prophylaxis of organ rejection in patients undergoing allogeneic renal, hepatic, or cardiac transplants. In transplant…

Discover arrhythmogenic right ventricular cardiomyopathy (ARVC), a genetic heart condition marked by fibrofatty replacement of right ventricular muscle leading to arrhythmias. This video explains the pathophysiology, diagnostic investigations, and treatment…

Explore hypertrophic cardiomyopathy, a genetic heart disorder marked by abnormal thickening of the myocardium that can impair cardiac function. This video explains its causes, symptoms like chest pain and syncope,…

Takotsubo cardiomyopathy also known as stress cardiomyopathy or apical ballooning syndrome is a heart condition often preceded by a stressful event such as a death of someone or a recent…

Explore the different types of cardiomyopathy—dilated, hypertrophic, and restrictive—and how they affect heart structure and function. This video explains their pathophysiology, key clinical features, and treatment strategies to manage symptoms…