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Archives: Videos

Tumour Lysis Syndrome (Tumor Lysis Syndrome) – pathophysiology, diagnosis and treatment

Armando Faigl April 4, 2020 No Comments

Tumour Lysis Syndrome is caused when tumour cells release their intracellular content into the bloodstream, either spontaneously or as a result of treatment leading to increased DNA – purine and…

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JAK (Janus Kinase Pathway) Inhibitor Tofacitinib – pharmacology, mechanism of action, side effects

Armando Faigl April 2, 2020 No Comments

Tofacitinib is an oral agent taken twice daily used to treat many rheumatological conditions mainly RA. Tofacitinib inhibits Janus kinase (JAK) signalling. Immune cells such as macrophages, monocytes and T…

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Sulphasalazine (DMARD) – Pharmacology, mechanism of action, metabolism, side effects

Armando Faigl March 23, 2020 No Comments

Learn about sulfasalazine, a disease-modifying antirheumatic drug (DMARD) used to treat inflammatory conditions like rheumatoid arthritis and IBD. This video explains its pharmacology, mechanism of action, metabolism, and potential side…

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Leflunomide (DMARD) pharmacology – mechanism of action, adverse effects and cholestyramine

Armando Faigl March 23, 2020 No Comments

Leflunomide is an immunosuppressant used to treat RA and psoriatic arthritis and Multiple sclerosis. Leflunomide is a prodrug that is rapidly and almost completely metabolized following oral administration to its…

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Hydroxychloroquine – Pharmacology and mechanism of action

Armando Faigl March 23, 2020 No Comments

Hydroxychloroquine explained: how this disease-modifying antirheumatic drug (DMARD) treats autoimmune conditions and why it’s first-line for systemic lupus erythematosus. Hydroxychloroquine (plaquenil) is an antimalarial with powerful immunomodulatory effects used in…

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Cyclophosphamide – pharmacology, mechanism of action, adverse effects

Armando Faigl March 23, 2020 No Comments

Learn about cyclophosphamide, a powerful alkylating agent used in cancer treatment and autoimmune diseases. This video explains its pharmacology, DNA-crosslinking mechanism of action, and potential adverse effects such as myelosuppression,…

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Calcineurin Inhibitors (Tacrolimus and Cyclosporine) IL2 – Mechanism of action, adverse effects

Armando Faigl March 23, 2020 No Comments

Calcineurin inhibitors such as tacrolimus and cyclosporine are immunosuppressants. They are used mainly to prevent organ transplant rejection in combination with mycophenolate and steroids as well used in severe atopic…

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Azathioprine – Pharmacology, mechanism of action, side effects,

Armando Faigl March 23, 2020 No Comments

Explore azathioprine, an immunosuppressive drug used in autoimmune diseases and organ transplantation. This video covers its pharmacology, mechanism of action in inhibiting purine synthesis, and common side effects including bone…

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COVID 19 SPANISH – resumen visual de la nueva pandemia de coronavirus

Armando Faigl March 22, 2020 No Comments

Conozca el COVID-19 en este resumen visual que explica la cronología, el ciclo de vida del coronavirus SARS-CoV-2 y su impacto en el cuerpo humano. Este video cubre la fisiopatología…

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COVID-19 a visual summary of the new coronavirus pandemic

Armando Faigl March 15, 2020 No Comments

Get a clear visual summary of COVID-19, covering how the SARS-CoV-2 virus spreads, infects cells, and affects the respiratory system. This video explains the timeline of infection, pathophysiology including ARDS,…

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Armando Hasudungan

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