Non-Hodgkin's lymphoma (NHL) is a diverse group of blood cancers that originate in the lymphatic system, primarily affecting lymphocytes. Clinically, it is significant due to its varying presentations, treatment responses, and prognoses, making accurate diagnosis and staging crucial for management. A key association is its link to immunosuppression, with conditions like HIV increasing the risk of developing aggressive forms of NHL, complicating patient care.

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