Armando Hasudungan

Biology and Medicine Tutorials

Lymphoma

Lymphoma is malignancy originating the lymph nodes. There are two types:

Classic Clinical Presentation 

  • Lymphadenopathy
  • Constitutional symptoms
    • Fever
    • Night sweats
    • Weight loss

Differential Diagnosis of Lymphadenopathy

  • Lymphoma
  • Leukaemia
  • Metastasis
  • Infection
  • Connective tissue disease - rheumatoid arthritis, SLE
  • Infiltration - sarcoidosis
  • Drugs - phenytoin
Hodgkin's lymphomaNon-Hodgkin's lymphoma
Bimodal Distribution
Risk FactorsEBVEBV may be associated with HIV
Lymph NodesContiguous and localizedNoncontiguous and peripheral
HistologyReed-Sternberg cellsMajority involve B cells
TreatmentABVDR-CHOP
Contents
cross