Axial disease

Axial disease refers to a group of inflammatory conditions primarily affecting the axial skeleton, including the spine and sacroiliac joints, with ankylosing spondylitis being a prominent example. It is clinically significant as it can lead to chronic pain, stiffness, and reduced mobility, impacting quality of life and functional ability. Early diagnosis and management are crucial to prevent complications such as spinal fusion and associated extra-articular manifestations like uveitis.