Hydralazine

Hydralazine is a vasodilator medication primarily used to treat hypertension and heart failure by relaxing blood vessels, which reduces systemic vascular resistance. Its clinical significance lies in its ability to lower blood pressure in patients who may not respond to other antihypertensives, particularly in cases of hypertensive emergencies or preeclampsia. A key association is its potential to cause drug-induced lupus erythematosus, especially with prolonged use.