Prednisolone is a synthetic glucocorticoid used to reduce inflammation and suppress the immune response in various conditions, including autoimmune diseases, allergies, and certain cancers. Its clinical significance lies in its ability to manage acute exacerbations and chronic inflammatory disorders effectively, although long-term use can lead to complications such as adrenal suppression, osteoporosis, and increased infection risk. Monitoring and tapering are essential to mitigate these risks.

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