Renal clearance is the volume of plasma from which a substance is completely removed by the kidneys per unit time, typically measured in millilitres per minute. It is crucial in assessing kidney function, guiding medication dosing, and diagnosing renal pathologies. For example, a reduced clearance of creatinine indicates impaired renal function, which can lead to complications such as fluid overload, electrolyte imbalances, and the progression of chronic kidney disease.
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