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Congenital Heart Defect

Overview Congenital heart disease (CHD) is the most common congenital disorder in newborns. Classification Acyanotic and Cyanotic Pulmonary blood flow Increased Decreased Normal Cyanotic (T's) Acynotic (D's) T etralogy of Fallot AS D T ransposition of the great vessles VS D T ricuspid atresia AVS D T runcus arteriosus Patent D uctus Arteriosus   Other:…

Complement Deficiencies

Overview Complement deficiencies are rare primary immunodeficiencies resulting from inherited absence or dysfunction of complement proteins, regulators, or receptors. They predispose to recurrent bacterial infections, autoimmune disease (particularly systemic lupus erythematosus–like syndromes), and in some cases angioedema. Complement proteins play a central role in innate immunity by opsonisation, chemotaxis, and direct lysis of pathogens via…

RA Related Pleural Effusion

Overview Rheumatoid pleural effusion (RPE) is an uncommon extra‑articular manifestation of rheumatoid arthritis (RA), occurring in ~2–5% of patients, more often in middle‑aged men with high rheumatoid factor (RF) titres, despite RA being more common in women. It typically presents during active disease or in patients with rheumatoid nodules, but can occasionally precede joint symptoms.…

Generalised Anxiety Disorder

DSM V categorise these as seperate disorders Depressive disorders Bipolar disorders Anxiety disorders Anxiety Disorders Generalised Anxiety Disorder Specific Phobia Agoraphobia Social Anxiety Disorder Panic Disorder This will mainly focus on Generalised Anxiety Disorder and touches on Panic Disorder . Overview Generalized anxiety disorder (GAD) can be defined as anxiety and worry about several events…

Acute Heart Failure

Overview Heart failure is a condition in which the heart does not pump enough blood to meet all the needs of the body. It is caused by heart muscle damage or dysfunction, valve problems, heart rhythm disturbances and other rarer causes. Acute heart failure can present as new-onset heart failure in people without known cardiac…

Pneumonia

Overview Pneumonia is infection in the lower respiratory tract and is characterised by fevers, purulent sputum, leucocytosis, low oxygen levels and new lung infiltrates (consolidation) on radiographic imaging. The infection is identified by the site of consolidation. Consolidation is where the lung tissue is filled with fluid (ie. water, blood, pus, microbes). Types of pneumonia…

Acute Kidney Injury (AKI)

Overview Acute kidney injury (AKI) (formerly acute renal failure) is the syndrome arising from a rapid fall in GFR (over hours to days). It is characterized by retention of both nitrogenous (including Urea and Creatinine) and non-nitrogenous waste products of metabolism, as well as disordered electrolyte, acid– base, and fluid homeostasis. AKI is neither a…

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