Chronic liver disease

Chronic liver disease refers to progressive liver damage lasting six months or longer, often resulting from conditions such as hepatitis, alcohol abuse, or non-alcoholic fatty liver disease. It is clinically significant due to its potential to lead to cirrhosis, liver failure, and hepatocellular carcinoma, necessitating careful monitoring and management. One key complication is portal hypertension, which can result in variceal bleeding and significant morbidity.