Methotrexate is an antimetabolite and immunosuppressive agent that inhibits dihydrofolate reductase, disrupting DNA synthesis and cellular replication. It is primarily used in the treatment of various cancers, autoimmune diseases, and ectopic pregnancies, making it crucial in managing conditions like rheumatoid arthritis and psoriasis. A key complication of methotrexate therapy is hepatotoxicity, which necessitates regular monitoring of liver function tests to prevent severe liver damage.
Please confirm you want to block this member.
You will no longer be able to:
Please allow a few minutes for this process to complete.