Autoantibodies are antibodies produced by the immune system that mistakenly target and attack the body’s own tissues, leading to autoimmune diseases. Their presence is clinically significant as they can help diagnose conditions such as systemic lupus erythematosus or rheumatoid arthritis, guiding treatment decisions. A key association is that elevated autoantibody levels can indicate disease activity and potential complications, such as organ damage or increased morbidity.

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