Acute kidney injury (AKI) is a rapid decline in kidney function, typically defined by an increase in serum creatinine or a decrease in urine output over hours to days. It is clinically significant due to its association with increased morbidity and mortality, often indicating underlying conditions such as sepsis or dehydration. A key complication of AKI is the risk of progression to chronic kidney disease, necessitating careful monitoring and management to prevent long-term renal damage.

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