Mesenteric Ischaemia

Aetiology and Risk Factors

Aetiology

Acute mesenteric ischemia can result from occlusion of a mesenteric vessel arising from an embolus, which may emanate from an atheroma of the aorta or cardiac mural thrombus, or from primary thrombosis of a mesenteric vessel, usually at a site of atherosclerotic stenosis. Embolic occlusion is more common in the superior mesenteric artery than the celiac or inferior mesenteric artery, presumably because of the less acute angle of the superior mesenteric artery off the abdominal aorta.

Clinical Manifestation

The hallmark of the diagnosis of acute mesenteric ischaemia is abrupt onset of intense cramping epigastric and periumbilical pain out of proportion to the findings on abdominal examination.

• Diarrhea
• Vomiting
• Bloating
• Melena

Examination

• Acutely ill, but the presentation may be subtle
• Shock is present in about 25% of cases

Diagnosis

Bowel Obstruction

Investigations

• FBC – may show decreased haemoglobin due to plasma loss and increase in WCC
• Amylase -elevated
• ABG – metabolic acidosis
• Abdominal X-ray – early may show gasless bowels.
• CT/MRI

References

UptoDate
Best Practice
Oxford Handbook Clinical Surgery
Oxford Handbook Clinical Medicine