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Armando Hasudungan

Overview

Coughing is a protective reflex, a component of normal respiratory function, it enables irritants and foreign bodies to be expelled from the vulnerable respiratory tract, however it can also be voluntarily generated and therefore has non-reflex elements to assist/enhance with mucocilliary clearance.

Definition

Acute cough: present up to 14 days/2 weeks
Prolonged acute cough: lasting 2 – 3 weeks
Chronic cough: present > 3 weeks

Cough Physiology
Physiology of Cough

The anatomical structures of the respiratory tract are very sensitive structures.

  • Larynx and Carina – especially sensitive (gateway to trachea and L + R main bronchus)
  • Trachea and Bronchi – very sensitive to light touch, a small amount of irritation can initiate the reflex
  • Terminal bronchioles and Alveoli – chemically sensitive to corrosive chemicals such as sulphur dioxide and chlorine gas

Approach

Alarm symptoms
Prominent dyspnoea, esp. at night or rest
Recurrent episodes of chronic wet or productive cough
Systemic Sx: fever, anorexia, wt. loss, failure to thrive
Feeding difficulties inc. choking or vomiting
Recurrent pneumonia
Additional breath sounds
Abnormal clinical respiratory examination
 Abnormal CXR
COMMON CAUSES OF COUGH
ConditionsHistoryExaminationWorkupAetiology
Asthma Expiratory wheezeOxygen, Fluids, bronchodilators +/-inhaled corticosteroids (depends on severity)Infection
Foreign bodySudden onset, history of chokingCough, StridorCT, bronchoscopyForiegn Body
Viral bronchiolitisCoryzal symptoms (2-3 days) followed by respiratory distressFine inspiratory crackles, expiratory wheeze, feverUsually non requiredRSV
Acute URTIsCoryzal symptoms   
Allergic rhinitis    
Croup (laryngotracheobronchitis)Barking cough, coryzaLow-grade fever, nasal flaring, respiratory retractions, stridorGenerally not indicatedGenerally not indicated

Young children develop 6-12 respiratory tract infections per year, usually accompanied by cough. In most children the cough is self-limiting (1-3) weeks.

CAUSES OF CHRONIC COUGH
ConditionHistoryExaminationWorkupAetiology
Smoking ExposureSmoking exposureNot significantGenerally not indicatedSmoking
GOR/GERHeartburn present, or if cough is worse at night or after eating specific foods   
SinusitisNasal discharge, obstruction, toothache, unilateral facial pain, headache, fever “Sinusitis is not associated with cough”Tender sinuses, fever, inflamed nasal mucosa, pus exudating from middle meatus, maxillary transillumination  
Post-nasal drip    
Bronchiectasis    

The most common causes of chronic cough in children are asthma, respiratory tract infections, and gastroesophageal reflux disease.

Management 

Flow chart of the management of wheeze in children
Management of persistent cough

Well child, normal examination

  • Watch and see
  • Avoid exposure to irritants such as cigarette smoke
  • Arrange follow up with paediatrician in 2-3 weeks.

Unwell child or abnormal examination 

  • These children will need further investigation and treatment and senior advice should be sought

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