Interleukin-6 (IL-6) is a pro-inflammatory cytokine produced by various cells, including macrophages and T cells, and plays a crucial role in immune response, inflammation, and hematopoiesis. In clinical practice, elevated IL-6 levels are associated with chronic inflammatory conditions, autoimmune diseases, and infections, making it a potential biomarker for disease severity. For instance, high IL-6 levels are linked to worse outcomes in COVID-19 patients, highlighting its importance in therapeutic targeting.

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