Lymphoma is a type of cancer that originates in the lymphatic system, primarily affecting lymphocytes, a form of white blood cell. It is clinically significant due to its varied presentations and potential to progress rapidly, necessitating prompt diagnosis and treatment. A key association is the distinction between Hodgkin lymphoma, characterized by Reed-Sternberg cells, and non-Hodgkin lymphoma, which encompasses a diverse group of malignancies with differing prognoses and treatment approaches.

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